Innate immune recognition of breast tumor cells mediates CCL22 secretion favoring Treg recruitment within tumor environment
نویسندگان
چکیده
منابع مشابه
Innate immune recognition of breast tumor cells mediates CCL22 secretion favoring Treg recruitment within tumor environment
Regulatory T cells (Treg) have been reported of poor prognosis for overall survival in primary breast tumors (BT). As CCL22 plays a major role in Treg recruitment within primary BT we deciphered the mechanisms involved in the CCL22 production by breast epithelial tumor cells and propose herein the major role of their innate immune recognition in this production.
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ژورنال
عنوان ژورنال: OncoImmunology
سال: 2012
ISSN: 2162-402X
DOI: 10.4161/onci.19680